RESEARCH FOR REAL-WORLD IMPACT:A Guide to Planning, Conduct & Dissemination of Pragmatic Research in Health

Introduction

Pragmatic research is intended to help support a decision by service and care providers – and policy makers, patients, and other stakeholders – on whether and in what context to adopt, deliver, or make use of an intervention. Of great importance is the fact that conducting research in diverse, real world settings helps to ensure that our evidence can be applied successfully across different populations and contexts – which is critical for promoting health equity.

This guide brings together both established and emerging pragmatic methods, measures, and models, many of which come from the blossoming field of dissemination and implementation (D&I) science. These methods help to ensure that pragmatic research is not seen as messy or poorly done research, but rather as both relevant and rigorous.

How to Use this Guide

[Info about ways to navigate (sequentially or by topic) and options for expanding/collapsing extra content (videos, publications, key links) based on our final web implementation]

Pragmatic Research Questions

Pragmatic Research Questions

View

The PRECIS-2 Framework

The PRECIS-2 Framework

View

Understanding Effectiveness and Implementation Research

Understanding Effectiveness and Implementation Research

View

Selecting Theories, Models and Frameworks

Selecting Theories, Models and Frameworks

View

Pragmatic Study Design

Pragmatic Study Design

View

Engaging Potential Adopters, Influencers and End Users

Engaging Potential Adopters, Influencers and End Users

View

Pragmatic Outcomes, Measures, & Data Collection

Pragmatic Outcomes, Measures, & Data Collection

View

Training, Skill-building, and Collaboration

Selecting Theories, Models and Frameworks

View

Partnerships & Infrastructure

Pragmatic Research Questions

View

Conducting Pragmatic Research

The PRECIS-2 Framework

View

Dissemination, Adaptation, Sustainability & Impact

Dissemination, Adaptation, Sustainability & Impact

View

TBD

Funding & Acknowledgements

Much of the content of this guide – and many of the resources linked in the guide – originated as part of the Colorado Pragmatic Research in Health Conference (COPRH Con). This guide and the initial three-year COPRH Con series were funded by the with funding from the Agency for Healthcare Research and Quality (R13HS027526).

Together, the conference series and this guide aim to:

  • Describe and promote use of pragmatic research methods, models, and measures to support translation of evidence-based practices, policies, and guidelines to clinical, community, and public health settings.
  • Build capacity for pragmatic research through use of web-based tools, templates, and guidance materials for application of pragmatic research methods.
  • Foster team science in use and testing of pragmatic research methods through creation and support of a virtual learning community

Key Partners

The Adult and Child Center for Outcomes Research and Delivery Science (ACCORDS) is a unique environment supporting innovative and interdisciplinary research across the CU Anschutz campus. ACCORDS brings together a large group of investigators from multiple disciplines, some who have their primary office at ACCORDS, and others who collaborate with ACCORDS personnel, programs and cores, while maintaining an off-site research home. Our methodologic cores provide support for the development of new projects, grant proposals for faculty, consultative support to investigators, as well as support our programmatic areas.

The Colorado Clinical and Translational Sciences Institute (CCTSI) supports translational research by providing resources, integrating facilities and services, developing innovative research tools and catalyzing interdisciplinary research programs.

Contributors: Bethany M. Kwan, COPRH Conference Chair, 2020-2022 (University of Colorado); Russell E. Glasgow (University of Colorado); Allison Kempe (University of Colorado); Amy Huebschmann (University of Colorado); Borsika Rabin (University of California San Diego); Elizabeth Juarez-Colunga (University of Colorado); Demetria McNeal (University of Colorado)

Last updated: April 28, 2023